Purpose: Examine the use of systemic phosphodiesterase inhibition (sildenafil) to clear central serous Nursing Balm chorioretinopathy (CSCR).Observations: In a long-standing CSCR patient, sildenafil produced a rapid resolution.When discontinued (dechallenge) the CSCR returned.When rechallenged, 9RG the CSCR again rapidly disappeared and did not recur in 5 months of continued therapy.
Conclusions: AND IMPORTANCE: Systemic sildenafil can cause rapid clearance of CSCR and can augment or replace other treatments.